Childlessness doesn't make people selfish; selfishness makes people selfish.
Creativity itself doesn't care at all about results - the only thing it craves is the process. Learn to love the process and let whatever happens next happen, without fussing too much about it. Work like a monk, or a mule, or some other representative metaphor for diligence. Love the work. Destiny will do what it wants with you, regardless.
Every few years, I think, 'Maybe now I'm finally smart enough or sophisticated enough to understand 'Ulysses.' So I pick it up and try it again. And by page 10, as always, I'm like, 'What the hell?'
I don't think you can come into your wisdom until you have made mistakes on your own skin and felt them in reality of your own life.