It's really easy to create a $1 billion company - you just have to solve a $10 billion problem.
Trust your gut instinct over spreadsheets. There are too many variables in the real world that you simply can't put into a spreadsheet. Spreadsheets spit out results from your inexact assumptions and give you a false sense of security. In most cases, your heart and gut are still your best guide.
I believe that entrepreneurs play an unmatched role and the accelerating pace of innovation is transforming the face of global challenges. You must think about the solution differently when you're trying to impact 1 billion people rather than affecting 1 million people.
Success is not about how much money we have in the bank, but it's about how many peoples' lives we have impacted through it. Success is experienced when we do things which are never done before.